





PN Skinbooster, also known as polynucleotide skin booster, is an injectable treatment made from highly purified polynucleotides. These are bioactive DNA fragments derived from purified salmon or trout, known for their ability to support skin repair and regeneration. The treatment is delivered through fine microinjections into the skin.
It is not a filler and does not change facial structure. While hyaluronic acid boosters mainly hydrate the surface, PN Skinbooster works from within, supporting your skin’s own repair process. It is often considered for dehydrated skin, dull skin, uneven texture, and overall skin quality, subject to doctor-led assessment.

Once delivered into the skin, polynucleotides act as biological stimulators. They encourage fibroblasts, the cells that produce collagen and elastin, to become more active. This supports skin repair and helps hold moisture within the skin, going deeper than what topical products can reach.
Because the treatment works through your skin’s own repair process, results build gradually. Improved hydration and texture may show within one to two weeks, with further changes in suppleness and skin quality developing over the following one to three months.
Once delivered into the skin, polynucleotides act as biological stimulators. They encourage fibroblasts, the cells that produce collagen and elastin, to become more active. This supports skin repair and helps hold moisture within the skin, going deeper than what topical products can reach.
Because the treatment works through your skin’s own repair process, results build gradually. Improved hydration and texture may show within one to two weeks, with further changes in suppleness and skin quality developing over the following one to three months.
Full Face: For overall improvement in skin hydration, texture, and tone.
Under-Eye Area: Often considered for fine lines and thin, dehydrated skin around the eyes.
Neck and Décolletage: May be explored when skin in these areas looks crepey, dry, or dull.
Hands: Suitable when the skin on the hands feels thin, dry, or uneven in texture.
Targeted Skin Areas: Certain areas of rough or uneven texture may be treated more specifically based on doctor assessment.
Your doctor will review your skin during consultation and put together a treatment plan based on where your skin needs the most support.
PN Skinbooster may be suitable for adults looking to improve skin quality through a regenerative, non-surgical approach. You may be suitable if you:
Your doctor will review your skin condition, medical history, and goals before recommending a plan that suits you.
PN Skinbooster is not the right fit for everyone. You may not be suitable if you:
A consultation at Dr Nazelia Clinic helps determine whether PN Skinbooster is appropriate for your skin, or whether a different approach would serve you better.
Before Treatment
Your session starts with a consultation. Your doctor will check your skin, go through your medical history, and talk through what you want to improve before confirming if PN Skinbooster is right for you.
During Treatment
Numbing cream is applied first for comfort. Once it takes effect, the polynucleotides are delivered through fine microinjections into the treated areas. Sessions usually take 30 to 45 minutes.
After Treatment
Most people get back to their day right after. Mild redness or slight swelling at the injection sites is common and usually clears within a day or two. Hydration and glow may show in the first one to two weeks, with smoother texture and firmer skin building over one to three months. A course of two to three sessions, spaced three to four weeks apart, is typical, with maintenance every six to twelve months.

Aftercare Guidelines
Simple aftercare helps your skin recover comfortably and get the most out of the treatment:
Short-Term Effects
Mild redness, slight swelling, or tenderness at the injection sites is normal and usually settles within one to two days. Small injection marks or minor bruising may appear but typically resolve on their own. If anything feels off or lasts longer than expected, contact Dr Nazelia Clinic so it can be looked into properly.